Steroid-Dependent Nephrotic Syndrome in a Child After an Allogeneic Bone Marrow Transplant: A Case Report

Nephrotic syndrome is a frequently encountered disease in children. It mostly responsive to high-dose steroids, with some requiring steroid-sparing immunosuppressive regimens, or further, renal biopsy if resistant steroid therapy. However, nephrotic children post-allogeneic bone marrow transplant rarely encountered. The authors report here child who developed for β-thalassaemia major, the suspicion of graft-versus-host that was difficult-to-treat, had frequent relapses multiple hospital admissions, and prolonged treatment course. For last 5 years, has been remission, on low dose prednisolone mycophenolate mofetil-based maintenance treatment.